Mitotic chromosomal assembly in vertebrates is regulated by condensin I and condensin II, which work cooperatively but have different chromosomal localization profiles and make distinct mechanistic ...

Figure 1: Schematic overview of the process used to derive and apply a gene expression signature of chromosomal instability. Figure 3: Metastatic foci expressed higher levels of the net CIN25 ...

Human egg cells are often prone to chromosomal errors. As women age, the error rate increases sharply — and can contribute to infertility, pregnancy loss, and ...

Researchers describe how the Epstein-Barr virus exploits genomic weaknesses to cause cancer while reducing the body's ability to suppress it. The Epstein-Barr virus (EBV) is easily spread through ...

Chemotherapy seeks to destroy tumor cells and has been a standard treatment for cancer for decades. However, it doesn't always work. "Chemotherapy is good for some patients, but it's not effective in ...

Higher levels of tetrahydrocannabinol, or THC — a chemical in marijuana that produces a euphoric feeling or “high” — was linked with changes in how eggs mature and a possible increase in chromosome ...

Researchers from the University of Vienna (Austria), National Institute of Technology—Wakayama College (NITW; Japan), and Shimane University (Japan) present the largest cephalopod genome sequenced to ...

“Therefore, EDA and aneuploidy rates represent two independent factors in determining the number of euploid embryos available for transfer and the overall likelihood of ART success.” “Therefore, EDA ...