If stretched out, human DNA would be about 2 meters long. For this long strand to fit inside the cell nucleus, which is about ...

After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to ...

Scientists have mapped out the molecular structure of a key part of our chromosomes called telomeres, which play a pivotal part in aging and cancer. Scientists from Nanyang Technological University, ...

One of the challenges of working with ancient DNA samples is that damage accumulates over time, breaking up the structure of the double helix into ever smaller fragments. In the samples we've worked ...

Scientists have discovered a new property of the molecular motors that shape our chromosomes. While six years ago they found that these so-called SMC motor proteins make long loops in our DNA, they ...

For decades, the Y chromosome – one of the two human sex chromosomes – has been notoriously challenging for the genomics community to sequence due to the complexity of its structure. Now, this elusive ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key repair process called homologous recombination, the cell uses loops in its ...

Research shows synthetic chromosomes can be transferred to human cells with potential to improve viral resistance ...

UC San Diego researchers uncover enzyme behind cancer genome chaos, pointing to potential therapies for aggressive tumors.

Small, cancer-associated DNA circles "hitchhike" on chromosomes during cell division to spread efficiently to daughter cells by co-opting a process used to maintain cellular identity through ...