ascopubs.org

Image-based collection to allow isolation and analysis of pure intact tumor cell populations from FFPE: Implications for more precise HER2 FISH analysis.

Irreversible panHER tyrosine kinase inhibitors (TKIs) to induce irreversible senescence in HER2 positive breast cancer cells. This is an ASCO Meeting Abstract from the 2016 ASCO Annual Meeting I. This ...
ascopubs.org

Development of an assay to predict oxaliplatin sensitivity from formalin-fixed, paraffin-embedded (FFPE) colorectal cancer tissues.

A single-arm trial of panitumumab in cetuximab refractory KRAS wild-type colorectal cancer. Background: Genomic profiling has improved our understanding of the underlying biology of tumors, accuracy ...
Labroots

In situ single-cell transcriptomic imaging in formalin-fixed paraffin-embedded (FFPE) tissues with MERSCOPE

Formalin-fixed paraffin-embedded (FFPE) tissues are the most widely used clinical sample types in histology and molecular diagnosis. However, due to RNA degradation and protein crosslinking, FFPE ...
News Medical

Efficient Extraction and Immunoprecipitation of Chromatin from Complex Formalin Fixed Paraffin Embedded Tissue

An invaluable source of RNA, DNA, and chromatin from historical and clinical samples is formalin fixed paraffin embedded (FFPE) tissue. Globally, tissue banks, hospitals, and laboratories are ...
Labroots

Visualizing in situ single-cell multi-omic gene expression from FFPE Tissue with MERSCOPE

In order to truly understand cell biology, researchers need easy-to-use tools that preserve the natural complexity of tissues while capturing the nuances of gene and protein expression. Vizgen’s in ...