A major focus in drug discovery involves the identification of compounds that reduce or modulate biological processes by altering the activity of cellular receptors or signal transduction components ...
Hu protein R (HuR) binds to the AU-rich element (ARE) in the 3'UTR to stabilize TNF-α mRNA. Here, we identified chemical inhibitors of the interaction between HuR and the ARE of TNF-α mRNA using RNA ...
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