Transcriptional Subtyping and CD8 Immunohistochemistry Identifies Patients With Stage II and III Colorectal Cancer With Poor Prognosis Who Benefit From Adjuvant Chemotherapy Initiatives such as The ...

An invaluable source of RNA, DNA, and chromatin from historical and clinical samples is formalin fixed paraffin embedded (FFPE) tissue. Globally, tissue banks, hospitals, and laboratories are ...

Next-generation sequencing (NGS) has transformed genomic research and clinical diagnostics by enabling rapid, high-throughput analysis of genetic material. The application of NGS to formalin-fixed ...

Randomized Phase III Trial of ABVD Versus Stanford V With or Without Radiation Therapy in Locally Extensive and Advanced-Stage Hodgkin Lymphoma: An Intergroup Study Coordinated by the Eastern ...

The authors have been funded, in part, with federal funds under grant 1R21 CA134359 from the NCI Innovative Molecular Analysis Technologies (IMAT) Program, and the Veterans Health Administration under ...

Formalin-based fixation and paraffin embedding (FFPE) is a common method to preserve clinical samples, and FFPE tumor samples serve as valuable study materials for clinical and translational medicine ...

It is a challenge to identify patients who, after undergoing potentially curative treatment for hepatocellular carcinoma, are at greatest risk for recurrence. Such high-risk patients could receive ...

Formalin-fixed paraffin-embedded (FFPE) tissues are the most widely used clinical sample types in histology and molecular diagnosis. However, due to RNA degradation and protein crosslinking, FFPE ...

Next-generation sequencing (NGS) has revolutionized genomics, transforming clinical diagnosis and treatment in different areas such as oncology, hematology and immunology. However, performing NGS on ...

Indeed, the gold-standard tissue preparation for proteome analyses was thought to be snap-freezing, Ginsberg says. He adds that comparing frozen samples to formalin-fixed ones was like comparing ...