Using high-speed atomic force microscopy (HS-AFM), the Kanazawa University team led by Mikihiro Shibata filmed the dynamic movements of CaMKII at the single-molecule level. The images revealed that a ...
Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have captured the first detailed molecular snapshots of human polynucleotide phosphorylase (hPNPase) in action, ...
A groundbreaking study has shed light on the critical role of a tRNA methylation enzyme, TRMT10A, in supporting brain function. The findings reveal how the absence of TRMT10A leads to a reduction in ...
Researchers have captured real-time "molecular movies" showing how an enzyme changes shape during catalysis. The study was ...
Enzymes catalyze chemical reactions in organisms - without which life would not be possible. Leveraging AlphaFold2 artificial intelligence, researchers at Charité – Universitätsmedizin Berlin have now ...
Nitrilases are a unique class of enzymes that catalyse the hydrolysis of nitrile compounds to yield the corresponding carboxylic acids or amides. Their application in biotransformation processes has ...
A new method can test the activity of thousands of RNA enzymes, called ribozymes, in a single experiment. The "RNA world" hypothesis proposes that the earliest life on Earth may have been based on RNA ...