Assistant Professor of Biomedical Engineering Yi Xue works on 2P-FOCUS, a new two-photon microscopy system, in her lab. The system promises novel insights into biological features that were once only ...

Two-photon microscopy is a type of fluorescence microscopy that, rather than exciting the sample with a single photon, makes use of multiple photons. The advantage over more traditional one-photon ...

A new two-photon fluorescence microscope developed at UC Davis can capture high-speed images of neural activity at cellular resolution thanks to a new adaptive sampling scheme and line illumination.

Intravital brain imaging is a valuable tool for studying neurons, glial cells, and their surroundings in living animals. It allows the investigation of neurological illnesses, therapeutic efficacy, ...

An all-in-one two-photon and/or confocal microscopy system called intravenous microscopy (IVM) was created and refined for in vivo longitudinal imaging of live animal models. This cutting-edge ...

The world of laser scanning microscopy is quickly evolving, thanks to the advent of fast and compact detector arrays. These arrays replace the typical single-element detector of traditional confocal ...

Figure 1 (a) Structure of the mesoscopic objective, (b) Aberration distribution of the mesoscopic objective, (c) Wide-field imaging system built with the mesoscopic objective, (d) Laser point-scanning ...

Researchers have developed a new two-photon fluorescence microscope that captures high-speed images of neural activity at cellular resolution. By imaging much faster and with less harm to brain tissue ...