Histone modification is an epigenetic mechanism that regulates gene expression by altering chromatin structure and DNA accessibility for transcription. Histone modification is regulated by various ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

Epigenetics, the study of changes in gene expression that are not caused by alterations in the DNA sequence, has emerged as a key player in the development and severity of type 2 diabetes. Epigenetics ...

The developmental period is a critical window during which environmental cues interact with the genome to shape lifelong trajectories of health and disease.

Epigenetic changes play important roles in cancer, metabolic and aging-related diseases, but also during loss of resilience as they cause the genetic material to be incorrectly interpreted in affected ...

Salt stress remains a critical challenge for plant growth, especially in crops like pea (Pisum sativum L.). This study explores the role of histone modifications in regulating pea's response to salt ...

During the process of metastasis, tumor cells inevitably encounter the stimulation of various oxidative stressors, resulting in the fluctuation of intracellular reactive oxygen species (ROS) levels.

Epigenetics is the study of the impact of human lifestyle and environmental factors on gene expression patterns. Epigenetic changes are dynamic and reversible and inherited somatically. These changes ...

New research in C. elegans from scientists at Howard Hughes Medical Institute (HHMI) helps explain how changes in the parents’ lysosomes that promote longevity are transferred to their offspring.

Researchers have revealed the mechanism of the drug valemetostat shown to be effective in treating certain types of cancer by targeting a protein modification (histone methylation) silencing the ...