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  1. MTHFR Gene Variant and Folic Acid Facts | Folic Acid | CDC

    May 27, 2025 · MTHFR Gene Variant and Folic Acid Facts Key points People with an MTHFR gene variant can process all types of folate, including folic acid. Getting 400 mcg of folic acid …

  2. MTHFR mutation: Symptoms, testing, and treatment

    Aug 21, 2025 · An MTHFR mutation is the mutation of a gene that regulates the production of a certain enzyme. The mutation can increase the risk of many health conditions.

  3. Methylenetetrahydrofolate reductase - Wikipedia

    Methylenetetrahydrofolate reductase (MTHFR) is the rate-limiting enzyme in the methyl cycle, and it is encoded by the MTHFR gene. [5] Methylenetetrahydrofolate reductase catalyzes the …

  4. MTHFR Gene Mutations: What You Need to Know - WebMD

    MTHFR gene mutation affects folate metabolism, linked to higher risk of cardiovascular issues, blood clots, and certain birth defects. It influences methylation and homocysteine levels.

  5. MTHFR Gene Mutation: Deficiency, Symptoms, Testing, Treatments

    Sep 9, 2024 · There are two common MTHFR mutations, known as C677T and A1298C. Having one copy of C677T or one copy of A1298C is not associated with health risks. Read on to …

  6. MTHFR Gene Mutations Explained: Symptoms, Risks & Testing …

    Jun 2, 2025 · Everything on MTHFR gene mutations, impact on health, symptoms, and testing. How MTHFR affects methylation, folate, and homocysteine—plus natural ways to manage it.

  7. MTHFR Gene Mutation: Symptoms, Testing, and Treatments

    Feb 25, 2025 · MTHFR is a gene everyone has. Some mutations of the MTHFR gene may be associated with health problems and complications in pregnancy. Learn about determining …

  8. MTHFR Gene Mutations and Disease - Verywell Health

    Nov 10, 2025 · MTHFR gene mutations are linked to many diseases to varying degrees, including heart disease, birth defects, Alzheimer's, and hypothyroidism.

  9. MTHFR gene: MedlinePlus Genetics

    The MTHFR gene provides instructions for making an enzyme called methylenetetrahydrofolate reductase. Learn about this gene and related health conditions.

  10. MTHFR Gene Polymorphisms: A Single Gene with Wide-Ranging …

    The enzyme 5,10-methylenetetrahydrofolate reductase (MTHFR) catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a process essential for the …